How It Works:

Bupivacaine belongs to class of medications called amide type of local anesthetics. It works by blocking the generation and conduction of nerve impulses, thereby leading to loss of pain, touch, and temperature sensations and muscle control in the area applied.

Side Effects:

slow heart rate, nausea, vomiting, urinary retention., low blood pressure, high blood pressure, dizziness, Paresthesia

Used For:

Bupivacaine is used to anesthetize certain parts of the body during surgery and to relieve pain during child birth and pain due to certain conditions like pain after surgery or pain in cancer patients.


  • Do not drive or operate machinery as bupivacaine injection can cause sleepiness.
  • Consult your doctor if you are on controlled sodium diet since it contains sodium; have respiratory, heart, kidney, liver problems or stomach tumor; swollen stomach due to excess fluid or have fluid in lungs; decreased blood volume.
  • Seek immediate medical attention if you feel dizzy, light headed, numbness of lips, tongue and around mouth, problem with sight or hearing after injection of bupivacaine.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently Ask Questions:

Q. Is bupivacaine safe during pregnancy?Bupivacaine can be taken during pregnancy if the benefit outweighs the risk. Please follow your doctor's advice regarding its use.
Q. Can bupivacaine be used during breastfeeding?Bupivacaine is safe for use during breastfeeding and should be used as per the doctor's advice.
Q. Is bupivacaine a controlled substance, narcotic, steroid, opioid, or neurolytic agent?Bupivacaine is not a controlled substance, narcotic, steroid, opioid or neurolytic agent. Bupivacaine is a local anesthetic.
Q. Is bupivacaine the same as Marcaine or lidocaine?Marcaine is the trade name of bupivacaine. Bupivacaine and lidocaine belongs to same class of drugs, however they differ in their some of the properties like duration of action and side effects.
Q. Is bupivacaine addictive?Bupivacaine is not an addictive drug.
Q. Does bupivacaine cause respiratory depression?Bupivacaine can cause respiratory depression if used in head or neck area.
Q. How long does bupivacaine take to work? How long does bupivacaine spinal or epidural injection last?Bupivacaine generally takes 5-10 min to work and lasts for about 4-8 hours. However the onset and duration depends on individual taking the medicine and method of injection.
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