Ciclopirox

How It Works:

Ciclopirox acts through the chelation of polyvalent metal cations, such as Fe3+ and Al3+. These cations inhibit many enzymes, including cytochromes, thus disrupting cellular activities such as mitochondrial electron transport processes and energy production. Ciclopirox also appears to modify the plasma membrane of fungi, resulting in the disorganization of internal structures. The anti-inflammatory action of ciclopirox is most likely due to inhibition of 5-lipoxygenase and cyclooxygenase. ciclopirox may exert its effect by disrupting DNA repair, cell division signals and structures (mitotic spindles) as well as some elements of intracellular transport.

Side Effects:

Pruritus, maceration of the skin., irritation

Used For:

Dandruff, pruritus, scalp disorders, seborrheic dermatitis, seborrhoea of scalp, tinea corporis.
This salt is found in the following medicine:
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