How It Works:

Dapsone slows the bacterial growth by preventing folic acid synthesis in susceptible organisms.

Side Effects:

nausea, inflammation of the liver and changes in liver function tests, vomiting, sensitivity to sunlight, loss of appetite, tingling in arms and legs due to nerve damage, difficulty sleeping, anemia, rapid heart beat., Dapsone syndrome, headache, jaundice, itchy skin rash

Used For:

Dapsone is mainly used to treat leprosy (infectious disease causing skin sores, nerve damage, and muscle weakness). It is also used to treat skin diseases like acne (pimples) and dermatitis herpetiformis (chronic autoimmune skin condition characterized by blisters with watery fluid, all over the body), to prevent malaria (along with pyrimethamine) and opportunistic infections especially pneumonia associated with AIDS (acquired immunodeficiency syndrome).


  • Dapsone should be used with caution in patients with heart or lung disease.
  • Regular blood counts should be performed during treatment with dapsone to check incidence of hemolysis (breakdown of red blood cells).
  • If you are pregnant or planning to become pregnant, but suffering from leprosy, your doctor may prescribe you folic acid supplements along with dapsone.

Frequently Ask Questions:

Q. Is dapsone safe during pregnancy?Dapsone should only be used if the potential benefits justify the potential risk to the baby. Please follow your doctor's advice regarding its use.
Q. Is it safe to use dapsone during breastfeeding?Dapsone is not safe for the baby and should not be used by women who are breastfeeding.
Q. Is dapsone a steroid, retinoid, immunosuppressant or sulfa drug?Dapsone is a sulfa drug used mainly to treat leprosy.
Q. Is dapsone available over the counter?No. Dapsone belongs to schedule H category of drugs and it is available only on valid prescription.
Q. Does dapsone cause itching, tiredness, weight gain, weight loss, hair loss or yeast infections?Dapsone may cause itching, tiredness, and loss of appetite. It is not reported to cause weight gain or loss, hair loss or yeast infections. Consult your doctor if you experience such side effects.
Q. Does dapsone topical work?Dapsone gel is used topically for the treatment of acne (pimples).
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