Eplerenone

How It Works:

Eplerenone lowers blood pressure and swelling by increasing the amount of urine, which removes extra water and certain electrolytes from the body. Eplerenone does this without loss of potassium from the body.

Side Effects:

Abnormal vaginal bleeding, Breast tenderness, Breast enlargement, Chest pain, Cough, Electrolyte imbalance, Diarrhoea, Abdominal pain, Dizziness, Fatigue, Headache, Altered heart rate, Increased creatine level in blood, Increased blood urea, Tingling sensation

Used For:

Eplerenone is used in the treatment of increased blood pressure , heart failure, cirrhosis and low potassium

Instructions:

  • Do consult your doctor before taking eplerenone if you have kidney or liver disease; high blood levels of fats (cholesterol and triglycerides); or diabetes.
  • Do not use eplerenone if you have very high blood levels of potassium or severe kidney problems.
  • Use of eplerenone is not recommended in children.
  • Do not stop taking eplerenone without consulting your doctor.
  • If you forget to take a dose of eplerenone, take it as soon as you remember (keeping a gap of at least 12 hours between two consecutive doses). Do not double the dose to make up for the missed dose.
  • Do consult your doctor before taking eplerenone, if you are pregnant, planning to become pregnant or are breastfeeding.

Frequently Ask Questions:

Q. Is eplerenone a diuretic/ potassium-sparing diuretic?
Yes. Eplerenone can increase urinary output and decrease excretion of potassium (potassium-sparing action) by blocking the biological effect of hormone aldosterone

Q. Is eplerenone a /beta blocker /blood thinner?
No. Eplerenone is an aldosterone receptor blocker that is used to improve conditions of heart failure after a heart attack and to lower high blood pressure. It has no known effect on beta adrenergic receptors and does not change the viscosity of blood

Q. Is eplerenone as steroid?
Yes. Eplerenone has a steroidal structure

Q. What is eplerenone used for/used to treat?
Eplerenone is used along with other drugs to prevent worsening and improve conditions of heart failure (due left ventricular dysfunction) after a heart attack (myocardial infarction) and in the treatment of high blood pressure

Q. Does eplerenone raise blood glucose/ cause erectile dysfunction/ weight gain/hair loss?
No. Increase in blood sugar, problems with erection (in men), changes in body weight and hair loss are not among the known side effects of eplerenone

Q. Does eplerenone cause gynecomastia?
Gynecomastia (enlargement of breasts in men) is an uncommon side effect of eplerenone affecting 1 to 10 users in 1,000

Q. How does eplerenone differ from spironolactone?
Eplerenone and spironolactone are both aldosterone antagonists. They differ with regards to their therapeutic use based up on clinical experiences.
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