Insulin Glargine

How It Works:

Lantus 100iu/ml cartridge replaces the insulin that the body would normally make. Insulin is critical for promoting the use and storage of all the major nutrients : glucose, fats and proteins.

Side Effects:

Altered blood lipids, Cough, Fat accumulation, Headache, Injection site itching, Limb swelling, Skin swelling, Skin redness, Weight gain, Abnormal sensation in skin

Used For:

Lantus 100iu/ml cartridge is used in the treatment of type 1 diabetes and type 2 diabetes


  • Avoid consuming alcohol as it may increase the chance of severe low blood sugar. 
  • Notify your doctor if you have any signs of troubled-breathing or rashes (severe and life-threatening allergy).      
  • Type 2 diabetes can be controlled with a proper diet alone or a diet along with exercise. Planned diet and exercising are always important when you have diabetes, even when you are taking antidiabetic medicines. 
  • Low blood sugar is life-threatening. Low blood sugar may occur due to:
    • Delay or missing a scheduled meal or snacks. 
    • Exercising more than usual. 
    • Drinking a significant amount of alcohol.
    • Using too much insulin.
    • Sickness (vomiting or diarrhea).
  • The main symptoms (alarming signs) of low blood sugar are fast heartbeat, sweating, cool pale skin, feeling shaky, confusion or irritability, headache, nausea, and nightmares. Make sure that you have access to quick-acting sugar sources that treat low blood sugar. Consuming some form of quick-acting sugars immediately after the appearance of the symptoms will prevent the low blood sugar levels from worsening. 

Frequently Ask Questions:

Q. Does insulin glargine/ Lantus insulin peak?
No, insulin glargine, whose action is steady and prolonged, has a relatively constant concentration time profile over 24 hours with no peaks

Q. Does insulin glargine/ Lantus insulin come in a pen?
Yes, insulin glargine is available in a pen style formulation

Q. Is insulin glargine/ Lantus insulin long acting?
Yes, insulin glargine has a relatively constant concentration time profile over 24 hours hence it is long acting

Q. How does insulin glargine work?
Insulin glargine is modified artificially prepared insulin (equivalent to human insulin) which is completely soluble in acidic pH of the glargine solution. Insulin glargine acts by replacing the normal production of insulin and by helping transfer sugar from the blood into other body tissues where it is utilized to generate energy. It also stops the liver from producing more sugar. After the injection of insulin glargine into the subcutaneous tissue (upper layer of skin), the acidic solution is neutralized leading to formation of micro particles (micro-precipitates) from which small amounts of insulin glargine are continuously released, providing a prolonged duration of action of insulin. Insulin glargine solutions have long and steady blood-sugar-lowering action

Q. How much does insulin glargine cost?
The cost of insulin glargine depends upon the various brands available in the market. Please read details on the package for the correct price of the produc

Q. Does insulin glargine/ Lantus insulin need to be refrigerated?
Unopened cartridges of insulin glargine/ Lantus must be stored in a refrigerator where the temperature is between 2 - 8°C. When the cartridge has been inserted into the injection pen, the cartridge pen combination should not be put in the refrigerator and should be kept at room temperature

Q. Does insulin glargine/ Lantus insulin cause weight gain?
There are no known effects of insulin glargine/lantus on weight gai

Q. Does insulin glargine/ Lantus insulin cause cancer?
There are no known effects of insulin glargine/ Lantus on causing cancer

Q. What is insulin glargine/ Lantus used for?
Insulin glargine/ Lantus is used to reduce high blood sugar (glucose) levels in people with diabetes mellitus. Insulin glargine is used to treat type 1 diabetes (condition in which the body does not produce insulin) and type 2 diabetes (condition in which the body does not use insulin normally)

Q. Is insulin glargine/ Lantus synthetic?
Yes, Insulin glargine is a genetically modified insulin that is grown in a laboratory, and is similar to human insulin

Q. Is insulin glargine/ Lantus safe?
Yes, insulin glargine is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Can insulin glargine/ Lantus be mixed?
Insulin glargine/ Lantus solution must not be mixed with any other glargine or insulin preparation. Always follow the instructions of doctor regarding the dosage, frequency, duration, or use of any concomitant medications

Q. How is insulin glargine/ Lantus made?
Insulin glargine/Lantus is produced by recombinant DNA technology with the help of a non-pathogenic (non-disease causing) laboratory strain of bacteria (Escherichia coli [K12]) as the production organism

Q. Is Lantus insulin (insulin glargine) the same as Levemir (insulin detemir)?
Both Lantus and Levemir are both long lasting forms of insulin (made by recombinant DNA technology) and are similar to human insulin. However, the duration of Levemir is slightly shorter than Lantus

Q. Is insulin glargine/ Lantus clear or cloudy?
Insulin glargine/ Lantus solutions should be clear. Do not use if insulin glargine preparations is no longer clear and colorless or if it contains particles.
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