How It Works:

Lapatinib belongs to a class of medications called antineoplastic kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply thus helping to slow or stop the spread of cancer cells.

Side Effects:

dry skin, trouble sleeping, feeling unusually tired or sleepy, a skin reaction on the palms of the hands or soles of the feet, cough, shortness of breath, hot flush, indigestion, nausea, nail disorders, liver problems, skin rash, vomiting, back/ hands/ feet/ joint pain, itching, shortness of breath., stomach pain, Diarrhea, sore mouth/mouth ulcers, irregular heartbeat, constipation, loss of appetite, unusual hair loss or thinning, nose bleed, headache

Used For:

Lapatinib is used alone or in combination with another anti-cancer medicine to treat certain types of breast cancer (HER2-overexpressing) which have spread beyond the original tumor or to other organs (advanced or metastatic breast cancer).


  • Before taking Lapatinib, tell your doctor, if you have heart disease such as heart failure or had a heart attack. You may need to undergo cardiac function tests prior to initiation of treatment and during treatment with Lapatinib to monitor your condition.
  • Lapatinib may cause liver damage which can be severe or life-threatening. Tell your doctor if you have or ever had liver disease.
  • Take precautions as Lapatinib often causes diarrhea, which can be severe.
  • You should be monitored for symptoms of pulmonary toxicity (dyspnea, cough, fever) and treatment should be discontinued if you experience severe symptoms.
  • You must use a reliable method of contraception to avoid becoming pregnant while on Lapatinib.
  • Do not drive or operate machinery as Lapatinib may cause extreme tiredness/weakness.

Frequently Ask Questions:

Q. Is lapatinib safe during pregnancy?Lapatinib should not be used during pregnancy unless clearly necessary or your doctor specifically recommends it.
Q. Is it safe to use lapatinib during breastfeeding?Lapatinib should not be administered to breastfeeding mothers.
Q. Is lapatinib cytotoxic/ chemotherapy? Lapatinib is not cytotoxic and not a chemotherapy drug.
Q. Is lapatinib a monoclonal antibody?Lapatinib is not a monoclonal antibody.
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