Mesna

How It Works:

Mesna reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) in the urine to form stable, nonurotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs.

Side Effects:

tachycardia, cough, yellowing of teeth., joint pain, Headache, abdominal pain, bronchospasm, exhaustion, diarrhea, limb pain, hypotension

Used For:

Cyclophosphamide induced hemorrhagic cystitis, ifosfamide induced hemorrhagic cystitis, prostate cancer.
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