Methoxsalen

How It Works:

Methoxsalen belongs to the group of medicines called psoralens (light-sensitive drug that absorbs ultraviolet light and acts like ultraviolet radiation). Methoxsalen works by modifying the way by which skin cells receive the ultraviolet light A (UVA) radiation, thereby clearing up the disease.

Side Effects:

new growth on the skin, nausea, change in the appearance of a mole, severe or persistent dizziness, Mild itching, severe itching or redness of the skin, trouble sleeping., blistering, depression, Severe allergic reactions, unusual swelling or blistering of the skin, temporary redness of the skin, burns on the treated area from overexposure to UVA or sunlight, nervousness

Used For:

Methoxsalen is used along with ultraviolet light (found in sunlight and some special lamps) in a treatment to treat vitiligo (a disease in which skin color is lost), and psoriasis (a skin condition associated with red and scaly patches), and treatment of white blood cells (called photopheresis) and is used to treat the skin problems associated with mycosis fungoides, which is a type of lymphoma.

Instructions:

  • Take this treatment (methoxsalen and UVA) two or three times a week with the treatment spaced at least forty-eight hours apart.  
  • Take this medication by mouth with food or milk, usually 2 to 4 hours before your UVA light treatment.
  • Do not sunbathe for 24 hours before taking methoxsalen. Wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen.
  • Use extra caution for at least 48 hours following each treatment.  After each treatment, cover your skin for at least 8 hours by wearing protective clothing.
  • Do not increase the amount of methoxsalen if you are taking or spend extra time in the sunlight or under an ultraviolet lamp.
  • Do not drive or operate machinery as methoxsalen may cause dizziness.
  • Not recommended for use in children younger than 12 years.
  • You will need to have an eye examination before starting methoxsalen and also once a year thereafter.

Frequently Ask Questions:

Q. Is methoxsalen safe in pregnancy?Methoxsalen may harm the baby. The drug should only be given if there is no other alternative drug. Please follow your doctor's advice regarding its use.
Q. Is it safe to use methoxsalen during breastfeeding?Methoxsalen should be given only if the potential benefit justifies the potential risk to the infant. Please follow your doctor's advice regarding its use.
Q. What is methoxsalen used for?Methoxsalen is used along with ultraviolet light (found in sunlight and some special lamps) in a treatment to treat vitiligo (a disease in which skin color is lost), and psoriasis (a skin condition associated with red and scaly patches), and treatment of white blood cells (called photopheresis) and is used to treat the skin problems associated with mycosis fungoides, which is a type of lymphoma.
Q. How does methoxsalen work?Methoxsalen works by modifying the way by which skin cells receive the ultraviolet light A (UVA) radiation, thereby clearing up the disease.
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