Milrinone

How It Works:

Milicor 10mg injection makes the heart pump blood with more force causing more blood to circulate through the body and also reduces the workload of the heart.

Side Effects:

Palpitations, Dizziness, Reduced blood platelets, Shortness of breath, Fainting, Headache, Tachycardia, Altered heart rate

Used For:

Milicor 10mg injection is used in the treatment of heart failure

Instructions:

  • Tell your doctor if you have a history of kidney problems, low potassium levels (hypokalemia), low blood pressure (hypotension), irregular heartbeat, heart valve disorders, myocardial infarction, heart attack or other heart problems.
  • You may be carefully monitored for blood pressure, heart rate, clinical state, ECG, fluid balance, electrolytes and renal function (i.e. serum creatinine).
  • The medicine cannot be given to children in case of an unstable heart rhythm and blood pressure.
  • Tell your doctor if your child has kidney problems, is a preterm infant or has a low birth weight or if your child has a certain heart problem known as Patent Ductus Arteriosus (a connection between 2 major blood vessels (aorta and pulmonary artery) which persists though it should be closed).
  • Consult your doctor if you are taking digoxin, diuretics,medications used to treat high blood pressure or chest pain (angina).
  • Seek medical advice, if you see signs such as feeling dizzy, lightheaded or fainting, fat or uneven heartbeat or chest pain after administration of milrinone.
  • Take precautions while using milrinone as it may decrease blood pressure (hypotension).
  •  Talk to your doctor if you are pregnant or planning to become pregnant or are breastfeeding.

Frequently Ask Questions:

Q. How does milrinone decrease preload and afterload/ does it need a central line/ does milrinone come in pill form?
Milrinone belongs to a class of medicines called phosphodiesterase inhibitors. It inhibits the enzyme phosphodiesterase-3, which eventually increases the contractility in the heart tissue, thereby, increasing the capacity of the heart to pump blood effectively. It is given as a drip (infusion) in the vein (intravenously) preferably via a central line. It does not come in the form of pill/tablet

Q. Does milrinone cause hypotension/ tachycardia/ increased heart rate/ increase blood pressure/ lower or decrease blood pressure?
Milrinone may lower/decrease your blood pressure (hypotension) and cause tachycardia and increased heart rate. It does not increase blood pressure.
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