How It Works:

Ranolazine belongs to class of medications called anti-anginals. It works by improving blood flow to help the heart work more efficiently.

Side Effects:

dizziness upon standing, sleepiness or drowsiness, low blood pressure, loss of appetite and/or weight loss, excessive sweating, indigestion, dry mouth, nausea, tremor, feeling swollen or bloated, visual disturbance, Dizziness, feeling tired or sluggish, muscle cramp, rapid weight gain, changes in sensation, allergy, dehydration, vomiting, stomach pain or discomfort, liver abnormality, ringing in the ears and/or feeling a spinning sensation, increase in creatinine or urea in your blood, blood in urine, pain in extremity, difficulty urinating, abnormal blood counts, hallucination, nose bleed, or gas, impotence., altered sensation, double vision, cough, dark urine, hot flushes, joint swelling, difficulty sleeping, blurred vision, feeling weak, confusion, itching, anxiety, headache, constipation, kidney failure

Used For:

Ranolazine is used alone or with other medications to treat ongoing angina (heart disease that causes intense chest pain).


  • Ranolazine should not be taken to treat sudden attack of chest pain (angina). Your doctor will advise you the exact treatment if you experience an attack of chest pain (angina).
  • Do not stop taking ranolazine without talking to your doctor.
  • Ranolazine may make you dizzy and lightheaded. Do not drive a car, operate machinery, or participate in activities requiring mental alertness and coordination until you know how this medication affects you.
  • Do not take a double dose to make up for a missed one.
Do not use ranolazine:
  • If you are allergic to any ingredient in ranolazine.
  • If you have liver cirrhosis; moderate or severe liver problems.
  • If you have severe kidney problems.
Consult your doctor before taking ranolazine:
  • If you have ever had an abnormal electrocardiogram (ECG).
  • If you are elderly.
  • If you have low weight.
  • If you have heart failure.

Frequently Ask Questions:

Q. Is ranolazine available in Canada/ Australia/ FDA approved?Ranolazine is an FDA approved drug and it is available in Canada and Australia.
Q. Is ranolazine generic?Ranolazine is a generic drug and it is available in different brand names (Ranolaz, Ranexa).
Q. Is ranolazine a blood thinner?Ranolazine belongs to class of medication called antianginals. It is not a blood thinner.
Q. Does ranolazine decrease mortality?Ranolazine is used for treatment of angina (chest pain) and it reduces the risk of mortality.
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