Zonisamide

How It Works:

Zonisamide is an anticonvulsant that belongs to a group of medicines called sulfonamides. It works by decreasing abnormal electrical activity in the brain.

Side Effects:

irritability, decreased blood levels of bicarbonate ., poor muscle coordination, confusion, depression, poor memory, loss of appetite, double vision, Agitation, dizziness, sleepiness

Used For:

Zonisamide is used to treat partial seizure (fits due to involvement of only one side of brain).

Instructions:

  • If your child (<12 years old) has been prescribed with zonisamide, ask your doctor for necessary precautions, as they are at greater risk of reduced sweating, heat stroke, pneumonia and liver problems.
  • Dress lightly during hot climates or when exercising and check carefully for signs of decreased sweating or heat stroke.
  • Drink sufficient water while taking zonisamide to reduce the risk of kidney stones and heat strokes.
  • Do not stop using zonisamide suddenly, even if you feel fine as stopping suddenly may cause increased seizures. 
  • Seek immediate medical attention if you develop serious and sometimes fatal skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), as zonisamide (sulfa medicine) is known to cause such side effects.
  • Inform your doctor and seek medical advice if you develop any signs of suicidal thoughts or actions, depressed mood, anxious state, restlessness, irritable behavior or any unusual change in mood or behavior; high fever or long lasting fever.
  • Do not drive or operate machinery as zonisamide may cause dizziness, drowsiness, or vision changes.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently Ask Questions:

Q. Is zonisamide safe during pregnancy? Zonisamide should only be used if the potential benefits justify the potential risk to the baby. Please follow your doctor's advice regarding its use.   Q. Is it safe to use zonisamide during breastfeeding? Zonisamide should only be used if the potential benefits justify the potential risk to the baby. Please follow your doctor's advice regarding its use.   Q. Is zonisamide a controlled substance/ addictive/ Narcotic/ gluten free/ generic? Yes, Zonisamide is a controlled drug. It is not an addictive or narcotic drug. It is gluten free and a generic drug.   Q. Is zonisamide used for weight loss or migraines? Zonisamide is not used to treat weight loss or migraines.   Q. Can I take ibuprofen/prednisone with zonisamide? Yes, Ibuprofen or prednisone can be taken with zonisamide.   Q. Does zonisamide cause weight gain/ kidney stones/hair loss/ weight loss/ diarrhea/ depression/ constipation/feeling high? Zonisamide commonly does not cause all the above mentioned side effects except depression. Please consult your doctor if you develop such side effects.
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